发明名称 2-pyrones
摘要 The present invention relates to the use of compounds of the formula (I) for the care, preservation or improvement of the general condition or appearance of the skin or hair, and to preparations comprising compounds of the formula (I).
申请公布号 US9499508(B2) 申请公布日期 2016.11.22
申请号 US201113991915 申请日期 2011.11.14
申请人 MERCK PATENT GMBH 发明人 Carola Christophe;Mueller Tatjana
分类号 C07D309/36;A61K8/49;A61Q19/06;A61Q19/08;C07D309/38;A23L1/03 主分类号 C07D309/36
代理机构 Millen White Zelano and Branigan, PC 代理人 Millen White Zelano and Branigan, PC ;Henter Csaba;Sopp John
主权项 1. A method for treating human skin or hair for reducing or combating cellulite or signs of cellulite and/or for reducing local fat accumulation and/or for combating time- and/or light-induced ageing processes of the skin or hair which comprises applying to human skin and/or hair at least one compound of the formula (I), which compound is active for achieving one or more of the above effects, where R1 stands for a straight-chain or branched C1- to C20-alkyl group, R2 stands for H orstraight-chain or branched C1- to C20-alkyl group, R4 stands for H,straight-chain or branched C1- to C20-alkyl group orstraight-chain or branched C2- to C20-alkenyl group having one or more double bonds, R3 stands for a radical selected from H,straight-chain or branched C1- to C20-alkyl group,straight-chain or branched C2- to C20-alkenyl group having one or more double bonds, where the alkenyl group may also be substituted by one or more saturated or unsaturated C3- to C12-cycloalkyl groups,straight-chain or branched C2- to C20-alkynyl group having one or more triple bonds,saturated or unsaturated C3- to C12-cycloalkyl group, where the rings may in each case also be bridged by —(CH2)n— groups where n=1 to 3,an acyl radical of the formula —C(═O)—R6, R6 stands for straight-chain or branched C1- to C20-alkyl group,a radical of the formula (II) in which X stands for straight-chain or branched C1- to C6-alkylene or straight-chain or branched C2- to C6-alkenylene and the radicals R5 are selected, independently of one another, from H, OH, straight-chain or branched C1- to C6-alkyl or straight-chain or branched O—(C1- to C6-alkyl).
地址 Darmstadt DE