| 摘要 |
<p>PURPOSE:To prepare the titled substance in high yield at a low cost, by cultivating a bacterium, belonging to the genus Arthrobacter, and capable of producing coproporphyrin III or a variant or variety strain thereof in a culture medium containing L-cystine and/or a specific amount of Mg<++>. CONSTITUTION:A bacterium capable of producing coproporphyrin III, e.g. Arthrobacter globiformis or Arthrobacter hyalinus, or a variant or variety strain of the parent strains is cultivated in a culture medium containing a carbon source, a nitrogen source, an inorganic salt, etc., preferably no iron salt, and in the presence of L-cystine and/or 0.5g/l or more Mg<++> added thereto.</p> |
