| 摘要 |
Compounds are described of the formula <IMAGE> in which R1 is H, C1-6 alkyl or C7-10 aralkyl; W is C1-7 alkylene; X is cis or trans -CH=CH- or -CH2CH2-; n is 1 or 2; Y is a saturated heterocyclic amino group having 5-8 ring members; R2 is (i) substituted or unsubstituted phenylalkyl, thienylalkyl or naphthylalkyl or (ii) substituted or unsubstituted cinnamyl; and their salts and solvates. These compounds inhibit blood platelet aggregation and bronchoconstriction and may be formulated for use as antithrombotic and antiasthmatic agents. |
