| 发明名称 | Diagnosis method and treatment for cancer using liv21 proteins and E2F1/E2F4 biomarkers | ||
| 摘要 | The invention concerns a novel diagnostic and/or prognostic test for cancer. More particularly, the invention concerns the human LIV21 protein, its use as cancer diagnostic and prognostic markers. The invention also concerns methods for treating cancers and neurodegenerative diseases as well as compositions therefor. | ||
| 申请公布号 | US9523688(B2) | 申请公布日期 | 2016.12.20 |
| 申请号 | US200611908103 | 申请日期 | 2006.03.07 |
| 申请人 | Faure Laurence | 发明人 | Faure Laurence |
| 分类号 | G01N33/53;G01N33/574;C07K14/47;C07K16/30;G01N33/50;G01N33/68;A61K38/00 | 主分类号 | G01N33/53 |
| 代理机构 | Young & Thompson | 代理人 | Young & Thompson |
| 主权项 | 1. A method for the detection of cancer cells in a biological sample from a patient, comprising detecting of the product of expression of the LIV21 gene in at least one of the nucleus and/or the cytoplasm of the cells in a sample of cells in the biological sample from said patient, the expression product comprising the peptide sequence of SEQ ID NO: 5 or the peptide sequence of SEQ ID NO: 3, wherein localization of said product of expression of the cytoplasm is indicative of the presence of said cancer cells in the biological sample, and localization of said product expression in the nucleus is indicative of the presence of non cancerous cells in the biological sample. | ||
| 地址 | Paris FR | ||