| 主权项 |
1. An in vitro method for diagnosing the prognosis of a test patient having renal cancer or the likelihood of renal cancer recurrence or metastatic progression in said test patient, comprising:
(1) measuring, in a sample obtained from said test patient, the expression levels of a panel of genes comprising at least 3 test genes selected from Table 1; (2) providing a test expression score by (a) weighting the determined expression of each gene in said panel of genes with a predefined coefficient (which may be 0), and (b) combining the weighted expression of each gene in said panel of genes to provide said test expression score, wherein said test genes are weighted to contribute at least 25% to said test expression score; and (3) diagnosing said test patient as having either (a) an increased likelihood of renal cancer recurrence or metastatic progression death based at least in part on said test expression score exceeding a first reference expression score or (b) no increased likelihood of renal cancer recurrence or metastatic progression based at least in part on said test expression score not exceeding a second reference expression score. |
