| 摘要 |
PURPOSE:To obtain the titled compound useful as an amino acid in high yield, by purifying impurities consisting essentially of isoleucine and/or leucine contaminating valine with a nonpolar porous synthetic adsorbent by simple procedures. CONSTITUTION:Impurities, contaminating valine, and consisting essentially of isoleucine and/or leucine are purified and removed. In the process,a nonpolar porous synthetic adsorbent, e.g. Diaion HP 20, SP 207 (manufactured by Mitsubishi Chemical Industried Ltd.) or XAD-4 or XAD-2000 (manufactured by Rohm and Haas Co.) is used to purify the valine. The above-mentioned method may be carried out by the batch or column method, but preferably the column method is used. The amount of the adsorbent to be used in the above-mentioned method is about 3-4 times based on the amount of an aqueous solution in about 30% concentration. The amount of the adsorbent may be smaller with decreasing concentration of the valine.
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