| 摘要 |
<p>PURPOSE:A hydrophobic and water-insoluble porous solid with a specific average pore diameter, to which an animal serum protein is adhered, is used as a T-cell separator to separate T-cells playing a role in immunological reactions such as inhibition of antibody production from a lymphocyte suspension. CONSTITUTION:An amimal serum protein, especially a serum protein from mammarian fetus, is adhered to a hydrophbic, water-insoluble porous solid with an average pore diameter of 500-5,000Angstrom to prepare a T-cell separateor. A column 3 with inlet and outlet 1, 2 of which at least outlet 2 has a filter 4 is filled with the above T-cell separator and the resultant device is brought into contact with a lymphocyte suspension in a solution containing more than 0.1g/dl of protein to separate T-cells in high purity and high yield without immunoligical stimulation by use of less amount of protein than in the conventional process rapidly, simply in sterility.</p> |
