发明名称 |
NOVEL COMPLEXES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL USE OF THEM. |
摘要 |
<p>Pullulan platinum complexes are new, in which the pullulan bears active sites of formula (Ia), (Ib), (Ic) or (Id): and one hydrogen atom of some or all of these active sites is replaced by a group of formula (IIa) or (IIb): (where L1 and L2 are each ammonia or a unidentate amine, or together are a bidentate amine; Y is an anionic ligand); or in the case of (Ic) two hydrogen atoms may be replaced by a group of formula (IV); or the hydrogen atom of two adjacent (Id) may be replaced by (IV). Prepn is by sulphation, sulphonation, phosphorylation or carboxylation of pullulan, followed by reaction with a platinum compound of formula (III): (where X1 and X2 are nitrato, or one is nitrato and the other is hydroxo or sulphato).</p> |
申请公布号 |
EP0270682(A1) |
申请公布日期 |
1988.06.15 |
申请号 |
EP19870903416 |
申请日期 |
1987.05.20 |
申请人 |
KURARAY CO., LTD. |
发明人 |
MORI, FUMIO;OKADA, MASAFUMI;MIKI, SHUJI;EBASHI, IWAO;NISHIDA, TAKASHI;KAWAI, KOUICHIRO;TASHIRO, TAZUKO;TSUKAGOSHI, SHIGERU |
分类号 |
C08B37/00 |
主分类号 |
C08B37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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