发明名称 |
Targeted conjugates and particles and formulations thereof |
摘要 |
Nanoparticles and microparticles, and pharmaceutical formulations thereof, containing conjugates of an active agent such as a therapeutic, prophylactic, or diagnostic agent attached to a targeting moiety, such as a somatostatin receptor binding moiety, via a linker have been designed. Such nanoparticles and microparticles can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer or infectious diseases. |
申请公布号 |
AU2015284236(A1) |
申请公布日期 |
2016.12.22 |
申请号 |
AU20150284236 |
申请日期 |
2015.06.30 |
申请人 |
Tarveda Therapeutics, Inc. |
发明人 |
Alargova, Rossitza G.;Bilodeau, Mark T.;Dunbar, Craig A.;Kadiyala, Sudhakar;Shinde, Rajesh R.;Lim Soo, Patrick;Sweryda-Krawiec, Beata;White, Brian H.;Bazinet, Patrick Rosaire;Wooster, Richard |
分类号 |
A61K9/14;A61K51/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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