发明名称 |
NOVEL LL-METHYLENE-OESTR-15-ENES, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS |
摘要 |
The present invention is concerned with novel 11-methylene-oestr-15-enes of the formula: <CHEM> wherein R1 = H or acyl with 1-18 C-atoms, preferably H, R2 = ethinyl, vinyl, chloroethinyl, allyl or propinyl; ethinyl being preferred, and R3 = O or H2, preferably O. Further the present invention is concerned with processes for the preparation of the above compounds and with pharmaceutical compositions comprising these compounds. The compounds possess powerful gestagenic properties and only slight androgenic side-effects. |
申请公布号 |
DE3665720(D1) |
申请公布日期 |
1989.10.26 |
申请号 |
DE19863665720 |
申请日期 |
1986.06.24 |
申请人 |
AKZO N.V. |
发明人 |
BERGINK, ENGELBERT WILLEM, DR. |
分类号 |
A61K31/575;A61K31/565;C07J1/00;C07J9/00;C07J11/00;C07J21/00;C07J33/00;C09J7/00;C12P7/02;C12R1/645;C12R1/80;(IPC1-7):C07J1/00 |
主分类号 |
A61K31/575 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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