METHODS FOR DETECTING AND/OR IDENTIFYING ADENO-ASSOCIATED VIRUS (AAV) SEQUENCES AND METHODS FOR ISOLATING NOVEL SEQUENCES IDENTIFIED THEREBY

摘要

PROBLEM TO BE SOLVED: To provide recombinant adeno-associated viruses comprising a novel capsid or portion thereof.SOLUTION: The recombinant adeno-associated virus (AAV) comprises AAVrh.34vp3 protein or AAVvp3 capsid protein having a specific amino acid sequence, where the recombinant AAV having an AAV capsid further comprises a minigene comprising AAV inverted terminal repeats (ITR) and a heterologous gene operably linked to a regulatory sequence which permits expression in a host cell.SELECTED DRAWING: None