发明名称 7-[(SUBSTITUTED)AMINO]-8-[SUBSTITUTED(CARBONYL)- METHYL-AMINO]-1-OXASPIRO[4.5]DECANES AS ANALGESIC AGENTS
摘要 <p>Substituted phenoxy-, 1-, and 2-naphthalenyloxy-, indenyl-, indolyl-, benzofuranyl-, and benzo¢b!thiofuranylcarboxamides of 7,8-(substituted-diamino)-1-oxaspiro¢4.5!decanes are useful as analgesic agents. A method of making the compounds, pharmaceutical compositions employing the compounds, and a method of alleviating pain in warm-blooded animals are also disclosed. The compounds have the general formula: wherein n, R1, R2, R3, x and Y are as defined in the disclosure and claims.</p>
申请公布号 CA1264321(A) 申请公布日期 1990.01.09
申请号 CA19860512571 申请日期 1986.06.26
申请人 WARNER-LAMBERT COMPANY 发明人 HORWELL, DAVID C.
分类号 A61K31/34;A61K31/38;A61K31/381;A61K31/40;A61K31/41;A61P25/04;C07D307/94;C07D333/00;C07D405/12;C07D407/12;C07D409/12;(IPC1-7):C07D307/94;C07D405/08;A61K31/33 主分类号 A61K31/34
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