VACCINE FOR GENERATING AN IMMUNOGENIC T CELL RESPONSE PROTECTIVE AGAINST A VIRUS

摘要

A vaccine for generating an immunogenic T cell response protective against a virus, such as a herpes virus, comprising an immunologically effective amount of (1) a peptide-fatty acid conjugate, the peptide having an amino acid sequence corresponding to the sequence of a fragment of a glycoprotein of the virus which produces a T cell response, or a synthetic replica of such fragment, (2) a liposome composition comprising a mixture of phosphatidyl choline, cholesterol and lysophosphatidyl choline, and (3) complete Freund's adjuvant.