Iontophoretic drug delivery packaging

摘要

The present invention relates generally to iontophoretic drug delivery systems for transdermal delivery of therapeutic agents and, more particularly, to packaging such systems for long shelf life and easy assembly for use. The system package includes an iontophoretic skin worn patch component that accommodates a power source, electronics, electrodes and a drug pack component that carries a therapeutic agent which is contained as a separate sealed component. The packaged system further provides for ease of assembly at the time of use.

主权项

1. An iontophoretic drug delivery system for pre-use assembly comprising:
(a) a drug pack component comprising one or more gel pads; (b) an iontophoresis patch component; (c) wherein said iontophoresis patch component is configured to align said gel pads of said drug pack component in conductive relation in an assembled state; and (d) an alignment structure to assist in assembling said components, wherein said alignment structure is selected from; (1) a folding support structure associated with said drug pack component and said iontophoresis patch component, said folding support structure comprising a separator component configured to be interposed between and thereby physically separate and protect said drug pack and iontophoresis patch components when said iontophoretic drug delivery system is present in a fully folded storage stage, wherein said folding support structure comprises a first panel having thereon said iontophoresis patch component, and a second panel having thereon said drug pack component comprising said gel gads and joined to said first panel on a first side of said second panel, and wherein said separator component comprises a third panel joined to said second panel on a second side of said second panel that is opposite said first side; and (2) a guide element for separate consecutive alignment of said drug pack component with said iontophoresis patch component; wherein said drug pack component comprises a drug pack support structure separate from the alignment structure, said iontophoresis patch component comprises an iontophoresis patch support structure separate from the alignment structure, and said alignment structure comprising said guide element comprises a flat substrate comprising spaced raised alignment members for aligning the drug pack component with the iontophoresis patch component; wherein said alignment structure comprises a multi-panel folding support structure associating said drug pack component said iontophoresis patch component and said separator component.