| 摘要 |
PCT No. PCT/FI92/00339 Sec. 371 Date Jul. 7, 1994 Sec. 102(e) Date Jul. 7, 1994 PCT Filed Dec. 10, 1992 PCT Pub. No. WO93/11757 PCT Pub. Date Jun. 24, 1993This invention relates to parenteral preparations of antiestrogens such as toremifene, desmethyl toremifene, tamoxifen or desmethyltamoxifen. The preparations can be emulsions, liposomes or aqueous solutions of cyclodextrin-drug complexes. Particularly the invention relates to a parenteral drug formulation comprising a complex having a 2-hydroxypropyl cyclodextrin component and including an active drug substance selected from the group consisting of toremifene, desmethyl toremifene, tamoxifen and desmethyltamoxifen or a pharmaceutically acceptable non-toxic salt thereof, said complex being present either in an aqueous solution or emulsion or loaded into a liposome. |
