| 摘要 |
PCT No. PCT/SE92/00558 Sec. 371 Date Feb. 18, 1994 Sec. 102(e) Date Feb. 18, 1994 PCT Filed Aug. 19, 1992 PCT Pub. No. WO93/04357 PCT Pub. Date Mar. 4, 1993A method of assaying for an analyte in a fluid sample comprises detecting the presence of the analyte by determining the resulting change in refractive index at a solid optical surface in contact with the sample, which change is caused by the analyte involving or influencing the binding or release of a refractive index-enhancing species to or from, respectively, the optical surface. Determination is performed with light having a wavelength at or near the maximum of the negative derivative of the absorptivity with respect to wavelength of the refractive index-enhancing species to obtain maximum sensitivity.
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