| 发明名称 |
BICYCLIC AMINO DERIVATIVES AND PGD2 ANTAGONIST CONTAINING THE SAME |
| 摘要 |
Compounds of general formula (I), salts thereof or hydrates thereof wherein (a) represents (b) or (c), for example, the compounds (d) and (e), which are useful as a PGD2 antagonist and thus usable in, for example, a remedy for systemic mastocytosis or systemic mast cell activation disorders, a drug for bronchoconstriction, an antiasthmatic, a drug for allergic rhinitis agent, a drug for allergic conjunctivitis, a drug for urticaria, a remedy for ischemia reflow disorders or an antiinflammatory agent. It is particularly useful in the treatment of nasal occlusion.
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| 申请公布号 |
WO9700853(A1) |
申请公布日期 |
1997.01.09 |
| 申请号 |
WO1996JP01685 |
申请日期 |
1996.06.19 |
| 申请人 |
SHIONOGI & CO., LTD.;OHTANI, MITSUAKI;ARIMURA, AKINORI;TSURI, TATSUO;KISHINO, JUNJI;HONMA, TSUNETOSHI |
发明人 |
OHTANI, MITSUAKI;ARIMURA, AKINORI;TSURI, TATSUO;KISHINO, JUNJI;HONMA, TSUNETOSHI |
| 分类号 |
A61K31/557;C07C233/52;C07C233/63;C07C233/74;C07C233/81;C07C233/84;C07C235/22;C07C235/36;C07C235/42;C07C235/54;C07C235/84;C07C237/38;C07C237/42;C07C245/08;C07C251/48;C07C251/86;C07C255/57;C07C271/24;C07C275/42;C07C281/14;C07C309/65;C07C311/13;C07C311/20;C07C311/29;C07C311/37;C07C311/43;C07C311/46;C07C311/51;C07C317/44;C07C323/62;C07C337/08;C07D207/34;C07D209/08;C07D209/10;C07D209/12;C07D209/42;C07D209/88;C07D213/56;C07D213/81;C07D215/36;C07D221/12;C07D235/06;C07D257/04;C07D261/18;C07D263/56;C07D263/57;C07D271/06;C07D271/10;C07D271/107;C07D275/02;C07D275/03;C07D277/20;C07D277/56;C07D279/20;C07D279/22;C07D285/06;C07D285/12;C07D295/192;C07D307/68;C07D307/84;C07D307/91;C07D311/12;C07D311/24;C07D311/82;C07D313/14;C07D317/48;C07D319/24;C07D333/18;C07D333/24;C07D333/32;C07D333/34;C07D333/36;C07D333/38;C07D333/62;C07D333/68;C07D333/76;C07D333/78;C07D337/14;C07D521/00;C07F9/535;(IPC1-7):C07C233/52;C07C311/06;C07C311/11;C07C311/19;C07D493/08;C07D495/08;A61K31/16;A61K31/18;A61K31/27;A61K31/33;A61K31/34;A61K31/35;A61K31/38 |
主分类号 |
A61K31/557 |
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