发明名称 |
Acyl transfer with stabilised transition complex using catalyst with catalytic imidazole (e.g. histidine) function |
摘要 |
The invention relates to a method of performing a chemical reaction between a reagent and a substrate, involving an acyl transfer mechanism, in the presence of an imidazole-based catalyst capable of forming a transition complex with the substrate. The catalytic imidazole function is provided by a chemical structure element comprising an optionally substituted imidazolyl group flanked on one or both sides by a group or groups capable of stabilizing the transition complex by molecular interaction with the acyl group. The invention also relates to such a designed chemical structure element, a method of producing it by recombinant DNA techniques and a vector therefor. |
申请公布号 |
AU2919497(A) |
申请公布日期 |
1997.12.05 |
申请号 |
AU19970029194 |
申请日期 |
1997.05.13 |
申请人 |
HOLDINGBOLAGET VID GOTEBORGS UNIVERSITET AB |
发明人 |
PER AHLBERG;LARS BALTZER |
分类号 |
C12N15/09;B01J31/02;C07B41/06;C07K1/04;C07K1/10;C07K14/00;C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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