发明名称 Method for producing doxazodin mesylate in a crystal modification designated as form a and intermediate product for producing the same
摘要 A process for preparing doxazosin mesylate in modification A which comprises dissolving doxazosin with methanesulfonic acid in methanol or a mixture of an aprotic, polar organic solvent and methanol, removing any turbidity from the resulting solution, and stirring the resulting clear solution until no further precipitate separates out, removing, washing with methanol, heating the precipitate in the moist state in ethanol and, after cooling, isolating the resulting product is described.
申请公布号 AU2275199(A) 申请公布日期 1999.07.26
申请号 AU19990022751 申请日期 1998.12.18
申请人 KNOLL AKTIENGESELLSCHAFT 发明人 PETER KLEIN;MARCO THYES;DIETER HLIX
分类号 A61K31/517;A61P9/12;C07D405/12;C07D405/14 主分类号 A61K31/517
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