| 发明名称 |
5-ARYL-1-IMINO-1-OXO-[1,2,4]THIADIAZINES |
| 摘要 |
The present invention provides a compound of formula I' having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease. |
| 申请公布号 |
EP3083644(A1) |
申请公布日期 |
2016.10.26 |
| 申请号 |
EP20140821587 |
申请日期 |
2014.12.17 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
GUBA, WOLFGANG;HAAP, WOLFGANG;KUGLSTATTER, ANDREAS;PETERS, JENS-UWE;OBST SANDER, ULRIKE;SCHNIDER, CHRISTIAN;WERMUTH, ROGER;WOLTERING, THOMAS |
| 分类号 |
C07D513/04;A61K31/549;A61K31/554;A61P25/28 |
主分类号 |
C07D513/04 |
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