发明名称 |
Gene encoding novel tsp1-like protein |
摘要 |
By an oligocap method originally developed for isolating full-length cDNA, a plural number of full-length cDNAs are isolated from a human placental tissue cDNA library. Among these cDNAs, a clone (hC-PLACE1009992) encoding a novel serine protease-like protein is isolated. Further, a mouse cDNA (mC-PLACE1009992) corresponding to this human cDNA is successfully isolated too. C-PLACE1009992 shows a change in the expression in the brain of a patient with Alzheimer's disease compared with the brain of a normal subject, which suggests that it might relate to Alzheimer's disease. |
申请公布号 |
AU6181500(A) |
申请公布日期 |
2001.02.19 |
申请号 |
AU20000061815 |
申请日期 |
2000.07.28 |
申请人 |
HELIX RESEARCH INSTITUTE |
发明人 |
TOSHIO OTA;TAKAO ISOGAI;TETSUO NISHIKAWA;KOJI HAYASHI;KAORU SAITO;JUN-ICHI YAMAMOTO;SHIZUKO ISHII;TOMOYASU SUGIYAMA;AI WAKAMATSU;KEIICHI NAGAI;TETSUJI OTSUKI;KOHJI MURAKAMI;KAZUHIRO YANO;KOUJI KANZAKI;YOSHIHISA INOUE |
分类号 |
A61K38/00;A61P25/28;A61P35/00;C07K14/47;C12N1/15;C12N1/19;C12N1/21;C12N15/12;C12N15/57;C12P21/08 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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