Methods and therapeutic compositions for treating cancer

摘要

Methods and therapeutic compositions for the treatment of cancer are disclosed. Specifically, peptides including beta-catenin binding domains and polynucleotide sequences encoding same, such as cadherins and o-catenins and polynucleotide sequences encoding same, effective in methods and compositions for treating cancers associated with abnormally high levels of beta-catenin, such as colon cancers and melanomas.