INTERMEDIATE OF CARBAPENEM ANTIBIOTICS AND PROCESS FOR THE PREPARATION THEREOF
摘要
PURPOSE: Provided are azetidinone compound of the formula(I) as an intermediate useful for the manufacture of carbapenem antibiotics and a process for the preparation thereof. CONSTITUTION: The azetidine compound is represented by the formula(I). It is useful as an intermediate for the manufacture of beta-methylcarbapenem antibiotics and manufactured by reacting 4-acetoxy-azetidine compound of the formula(II) and alpha-halo propionic acid amide compound of the formula(III).
申请公布号
KR20020079654(A)
申请公布日期
2002.10.19
申请号
KR20020052421
申请日期
2002.09.02
申请人
DONG WHA PHARM. IND. CO., LTD.;KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
发明人
JUNG, HUI JEONG;JUNG, WON JANG;JUNG, YONG HO;KIM, BONG JIN;KIM, EUN JEONG;KIM, JAE HAK;KWAK, HYEON JEONG;LEE, CHEOL HAE;LEE, JIN SU;PYUN, DO GYU;SONG, SIN SEOP