Method for separating lactone-containing high-molecular weight compounds

摘要

A method for separating a lactone-containing compound comprising subjecting a mixture of a lactone-containing compound having a basic chemical structure of 1,14-dihydroxy-12[2-(4-hydroxy-cyclohexyl)-1-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo-[22.3.1.04.9 ]octacos-18-ene-2,3,10,16-tetraone and, at least one of a C2-6 alkenyl group and a C1-6 alkoxy group as its side-chain, and its analogous compound(s) to either one or both steps in any order of a step (A) for absorbing the mixture to a nonionic adsorption resin and eluting with an aqueous solvent containing silver ions, and a step (B) for adsorbing the mixture to a basic active alumina and eluting with an organic solvent to separate each of the compounds.