| 摘要 |
Disclosed are compounds of Formula (I): wherein B, X, Z, D, G, R, R1, R1', R11, m, n, p, and q are as described in the specification. The compounds are useful in treating diseases that are mediated by the MC-4 and/or the MC-3 receptor. As such, the invention is directed to a manufacture of a medicament for treating disorders such as obesity, anorexia, cachexia, CNS depression, behavior-related disorders, memory-related disorders, cardiovascular function, inflammation, sepsis, septic shock, cardiogenic shock, hypovolemic shock, sexual dysfunction, erectile dysfunction, muscle atrophy, diseases associated with nerve growth and repair, and intrauterine fetal growth. Also disclosed are pharmaceutical compositions comprising the compounds of Formula (I).
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