ANTIBODIES

摘要

The present invention relates to antibodies, e.g., full length antibodies or antigen binding fragments thereof, that specifically bind to BCMA (B-Cell Maturation Antigen) and CD3 (Cluster of Differentiation 3). The invention also relates to antibody conjugates (e g., antibody-drug-conjugates) comprising the BCMA antibodies, compositions comprising the BCMA antibodies. The invention further relates to heteromultimeric antibodies that specifically bind to CD3 and a tumor cell antigen, (e.g., bispecific antibodies that specifically bind to CD3 and BCMA). Compositions comprising such heteromultimenc antibodies and methods for producing and purifying such heterodimeric antibodies are also provided.