发明名称 DERIVADOS DE UREIA E URETANA COMO INIBIDORES DE INTEGRINAS
摘要 Novel urea and urethane derivatives of general formula (I) in which R1, R2, R3, R5, R5', X, Y, B, m, n and o are as defined in Patent Claim 1 , and physiologically acceptable salts or solvates thereof are integrin inhibitors and can be employed for combating thromboses, cardiac infarction, coronary heart disease, arteriosclerosis, inflammation, tumors. Osteoporosis, infections and restenosis after angioplasty or in pathological processes maintained or propagated by antiogenesis.
申请公布号 PT1343764(E) 申请公布日期 2005.01.31
申请号 PT20010271360T 申请日期 2001.11.30
申请人 MERCK PATENT GMBH 发明人 ALFRED JONCZYK;STAEHLE, WOLFGANG;SCHADT, OLIVER;GOODMAN, SIMON
分类号 A61K31/4184;A61K31/44;A61K31/4402;A61P1/04;A61P7/02;A61P9/00;A61P9/04;A61P9/10;A61P9/14;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P19/10;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P35/04;A61P41/00;A61P43/00;C07D213/74;C07D235/30;(IPC1-7):C07D213/74 主分类号 A61K31/4184
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