| 发明名称 |
BETA-AMINO TETRAHYDROIMIDAZOLO(1,2-A) PYRAZINES AND TETRAHYDROTRIOAZOLO (4,3-A)PYRAZINES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES |
| 摘要 |
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in whichthe dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the useof these compounds and composition in the prevention of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. |
| 申请公布号 |
BG108493(A) |
申请公布日期 |
2005.04.30 |
| 申请号 |
BG20030108493 |
申请日期 |
2003.12.22 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
EDMONDSON SCOTT;FISHER MICHAEL;KIM DOOSEOP;MACCOSS MALCOLM;PARMEE EMMA;WEBER ANN;XU JINYOU |
| 分类号 |
A61K31/498;A61K31/4985;A61K45/00;A61K45/06;A61P1/02;A61P1/04;A61P3/04;A61P3/06;A61P3/10;A61P5/06;A61P5/28;A61P5/50;A61P7/00;A61P9/08;A61P9/10;A61P9/12;A61P13/08;A61P13/12;A61P15/16;A61P19/10;A61P25/00;A61P25/28;A61P27/02;A61P31/18;A61P35/04;A61P37/02;A61P43/00;C07D487/04 |
主分类号 |
A61K31/498 |
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