摘要 |
This invention relates to a novel microbiological process for the oxygenation of N-benzoyl-N,2,3,3-tetramethyl-exo-2-norbornanamine to obtain N-benzoyl-exo-6-hydroxy-N,2,3,3-tetramethyl-exo-2-norbornanamine and N-benzoyl-trans-7-hydroxy-N,2,3,3-tetramethyl-exo-2-norbornanamine, each of which are chemically converted to novel derivatives. These novel bioconversion products and their derivatives are active hypotensive agents and central nervous system stimulants.
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