发明名称 |
Fumarate-CO-releasing molecule hybrids, their use in the treatment of inflammatory or cardiovascular diseases and their process of preparation |
摘要 |
The present invention relates to hybrid fumarate-CO-releasing molecules capable of increasing heme oxygenase-1 (HO-1) activity and HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic applications, in particular their use in the treatment of inflammatory or cardiovascular diseases. |
申请公布号 |
AU2015233336(A1) |
申请公布日期 |
2016.09.29 |
申请号 |
AU20150233336 |
申请日期 |
2015.03.20 |
申请人 |
Centre National de la Recherche Scientifique (CNRS);Institut National de la Sante et de la Recherche Medicale (INSERM);Universite Paris Est Creteil Val de Marne |
发明人 |
Motterlini, Roberto;Foresti, Roberta;Martens, Thierry;Rivard, Michael |
分类号 |
C07F13/00;A61K31/28;A61K31/295;A61K33/24;A61K33/26;A61K33/32;A61P9/00;A61P29/00;C07F15/00;C07F15/02;C07F15/06 |
主分类号 |
C07F13/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|