| 摘要 |
1535967 Anti - lipidemic pharmaceutical compositions containing amino-benzoic acid derivatives AMERICAN CYANAMID CO 16 Feb 1976 [12 March 1975] 06047/76 Heading A5B [Also in Division C2] Pharmaceutical compositions comprise a compound of formula I: wherein R 1 is selected from hydrogen, (C 1 -C 6 ) alkyl, benzyl, di(C 1 -C 6 ) alkylaminoethyl and (C 1 -C 6 ) alkoxyethyl; R 2 is selected from aryl and substituted aryl wherein the substituents are selected from halo, alkyl, alkoxy and benzyloxy, A is selected from C n H 2n , wherein n=1-16 and C n H 2n-2 wherein n=3-16; or a pharmaceutically acceptable salt thereof; in conjunction with a pharmaceutically acceptable carrier or diluent excluding in the compositions containing p - [(3-phenylpropyl) amino] benzoic acid; p-benzylaminobenzoic acid; ethyl-p-benzylaminobenzoate; p-[(p - methoxybenzyl) amino] benzoic acid; ethyl-p-(#-phenethylamino) benzoate; p-(#-phenethylamino) benzoic acid; and p-[#-(3, 4-dimethoxyphenyl) ethylamino] benzoic acid wherein the carrier or diluent is non sterile water or a non sterile simple organic solvent. The compositions have use in treatment of hyperlipidemia. |
