发明名称 |
IMPROVED PROCESSING OF RECOMBINANT HUMAN G-CSF |
摘要 |
A G-CSF precursor comprising a signal peptide and a G-CSF peptide, wherein the signal peptide has the sequence of the human wild-type signal peptide of the human G-CSF/b molecule with at least one of the following mutations: - deletion of Glu29, - insertion of G1u26, - substitution Lys11Leu, - substitution His21Phe, and - substitution Gln28Leu. |
申请公布号 |
CA2738116(C) |
申请公布日期 |
2016.10.18 |
申请号 |
CA20092738116 |
申请日期 |
2009.10.02 |
申请人 |
OCTAPHARMA BIOPHARMACEUTICALS GMBH |
发明人 |
SCHROEDER, CAROLA;CASADEMUNT, ELISABETH;SOEHLEMANN, PETER;LEHNERER, MICHAEL |
分类号 |
C07K14/535 |
主分类号 |
C07K14/535 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|