发明名称 INJECTABLE FORMULATIONS FOR TREATING CANCER
摘要 The present invention provides injectable formulations of (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol and hydrates thereof and methods for treating disorders in which DOT1-mediated protein methylation plays a part, such as cancer and neurological disorders.
申请公布号 EP2968390(A4) 申请公布日期 2016.10.26
申请号 EP20140770498 申请日期 2014.03.14
申请人 EPIZYME, INC. 发明人 OLHAVA, EDWARD JAMES;DOVLETOGLOU, ANGELOS;REHLANENDER, BRUCE
分类号 A61K9/08;A61K31/7076;A61K47/40 主分类号 A61K9/08
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