摘要 |
PURPOSE:To obtain the titled compound under relatively mild condition without using particular solvent and expensive surfactant, by accelerating the nucleophilic substitution reaction with fluoride ion by the composite action of an alkali metal fluoride and an alkaline earth metal fluoride. CONSTITUTION:An alkyl fluoride is produced from an alkyl halide or a sulfonic acid alkyl ester, or an acyl fluoride is produced from an acyl halide, or sulfonyl fluoride is produced from a sulfonyl halide by using a mixture of an alkali metal fluoride and an alkaline earth metal fluoride, e.g. potassium fluoride- calcium fluoride, sodium fluoride-calcium fluoride, etc. |