Methods of using adipose derived regenerative cells to promote restoration of intevertebral disc

摘要

Regenerative cells present in adipose tissue are used to treat patients, including patients with musculoskeletal diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, regenerative cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic musculoskeletal benefit.

主权项

1. A method for promoting restoration of an intervertebral disc in a subject comprising:
identifying a subject in need of intervertebral disc restoration; obtaining a unit of adipose tissue from said subject; processing said unit of adipose tissue obtained from said subject by separating adipose-derived cells comprising stem and progenitor cells from mature adipocytes and connective tissue, and washing, separating and concentration said adipose-derived cells to obtain a concentrated population of cells that comprises stem cells and endothelial progenitor cells; and administering said concentrated population of cells to the intervertebral disc of said subject without culturing the concentrated population of cells prior to administration to the subject.