| 摘要 |
<p>TITLE OF THE DISCLOSURE NEW 2,5-DIARYL TETRAHYDROFURANS AND ANALOGS THEREOF AS PAF-ANTAGONISTS Analogs of 2,5-Diaryl tetrahydrofurans which were substituted or unsubstituted at 3,4-positions were prepared. These compounds are found to have potent and specific PAF (Platelet Activating Factor) antagonistic activities and thereby useful in the treatment of various diseases or disorders mediated by the PAF, for example, inflammation, cardiovascular disorder, asthma, lung edema, adult respiratory distress syndrome, pain, and aggregation of platelets.</p> |
