发明名称 |
METHOD FOR LABELLING SUBSTANCES CONTAINING AMINO GROUPS, INCLUDING CELLS SUCH AS BLOOD CELLS, WITH <99m>Tc AND KIT FOR CARRYING OUT THIS METHOD |
摘要 |
The invention relates to a method for labelling substances, including cells such as blood cells, which contain one or more amino groups, with a radioisotope, the substance to be labelled being combined in the presence of a reductor with <99m>TcO4 ions and the reductor used being at least one borohydride, to a kit for carrying out said method, which kit comprises at least a container, which contains a freeze-dried mixture of a borohydride, a tin(II) salt and a buffer, and to a freeze-dried mixture at least consisting of borohydride, tin(II) salt and buffer for use in labelling reactions. |
申请公布号 |
WO9117999(A1) |
申请公布日期 |
1991.11.28 |
申请号 |
WO1991NL00080 |
申请日期 |
1991.05.15 |
申请人 |
ACADEMISCH ZIEKENHUIS LEIDEN |
发明人 |
PAUWELS, ERNEST, KAREL, JACOB;FEITSMA, ROLF, IDE, JOHANNES |
分类号 |
A61K51/12;C07B59/00;C07F13/00 |
主分类号 |
A61K51/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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