发明名称 METHOD FOR LABELLING SUBSTANCES CONTAINING AMINO GROUPS, INCLUDING CELLS SUCH AS BLOOD CELLS, WITH <99m>Tc AND KIT FOR CARRYING OUT THIS METHOD
摘要 The invention relates to a method for labelling substances, including cells such as blood cells, which contain one or more amino groups, with a radioisotope, the substance to be labelled being combined in the presence of a reductor with <99m>TcO4 ions and the reductor used being at least one borohydride, to a kit for carrying out said method, which kit comprises at least a container, which contains a freeze-dried mixture of a borohydride, a tin(II) salt and a buffer, and to a freeze-dried mixture at least consisting of borohydride, tin(II) salt and buffer for use in labelling reactions.
申请公布号 WO9117999(A1) 申请公布日期 1991.11.28
申请号 WO1991NL00080 申请日期 1991.05.15
申请人 ACADEMISCH ZIEKENHUIS LEIDEN 发明人 PAUWELS, ERNEST, KAREL, JACOB;FEITSMA, ROLF, IDE, JOHANNES
分类号 A61K51/12;C07B59/00;C07F13/00 主分类号 A61K51/12
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