IN VIVO EXTRACTION OF INTERSTITIAL FLUID USING HOLLOW MICRONEEDLES
摘要
A transdermal and/or intradermal diagnostic device comprising a combined hollow microneedle interstitial fluid (IF) extraction device and a detector can monitor biomarkers in-situ. For example, electrode transducers with optimally arrayed and designed microneedles can be combined with a suitable pumping method to determine biomarker levels in human subjects under intense physical exertion to monitor metabolic stress and fatigue. The device can perform real-time, in-situ measurements of lactate in human subjects. Monitoring of other biomarkers is straightforward.
申请公布号
WO2016164208(A1)
申请公布日期
2016.10.13
申请号
WO2016US24747
申请日期
2016.03.29
申请人
SANDIA CORPORATION;STC.UNM
发明人
POLSKY, Ronen;MILLER, Philip, Rocco;BACA, Justin, T.