发明名称 COMBINATION THERAPY OF BENDAMUSTINE WITH AFUCOSYLATED CD20 ANTIBODY
摘要 PROBLEM TO BE SOLVED: To provide a combination therapy of bendamustine with afucosylated CD20 antibody for the treatment of cancer, specifically, the combination treatment of CD20 expressing cancer using bendamustine and afucosylated B-Ly1 antibody.SOLUTION: In order to produce a cancer treatment drug to be used in combination with bendamustine, an afucosylated CD20 antibody is used in which, at Asn297, the amount of fucose is 60% or less of the total oligosaccharide (sugar) content.SELECTED DRAWING: None
申请公布号 JP2016222673(A) 申请公布日期 2016.12.28
申请号 JP20160118739 申请日期 2016.06.15
申请人 ROCHE GLYCART AG 发明人 FRANK HERTING;CHRISTIAN KLEIN
分类号 A61K39/395;A61K31/4184;A61P35/00 主分类号 A61K39/395
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