发明名称 IMPROVED EXTENDED-ACTION TILMICOSIN AND USE THEREOF IN TREATMENT OF BOVINE RESPIRATORY DISEASE COMPLEX (BRD) AND IN DRY COW PERIOD
摘要 The invention relates to an improved long-acting or extended-release tilmicosin formulation comprising: tilmicosin phosphate in a concentration between 35 and 50% by weight of the total composition; a first co-solvent in a concentration between 8 and 20% by volume, said first co-solvent being propylene glycol; a second co-solvent in a concentration between 5 and 15% by volume, said second co-solvent being ethyl alcohol; and an emulsifier in a concentration between 1.5 and 15% by weight of the total composition, said emulsifier being poloxamer. The invention also relates to the method for producing said improved long-acting tilmicosin formulation.
申请公布号 US2016367580(A1) 申请公布日期 2016.12.22
申请号 US201514890827 申请日期 2015.02.18
申请人 UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO 发明人 SUMANO LOPEZ Hector Salvador;GUTIERREZ OLVERA Lilia
分类号 A61K31/706;A61K47/10 主分类号 A61K31/706
代理机构 代理人
主权项 1. A new tilmicosin formulation having the formulawherein said tilmicosin has been formulated for improved extended action or release.
地址 Distrito Federal MX