发明名称 |
WATER SOLUBLE REACTIVE DERIVATIVES OF CARBOXY POLYSACCHARIDES AND FIBRINOGEN CONJUGATES THEREOF |
摘要 |
The present invention provides water-soluble reactive esters of carboxy polysaccharides and derivatives thereof. The reactive carboxy polysaccharide derivatives are useful per se in aqueous solutions or specifically for the formation of water-soluble covalent fibrinogen conjugates. A preferred conjugate is a hyaluronic acid-fibrinogen conjugate and fibrin adhesive, clot or matrix derived from it. Methods of preparation and methods of use in tissue repair and regeneration are also disclosed. |
申请公布号 |
EP2106263(B1) |
申请公布日期 |
2016.12.21 |
申请号 |
EP20080702616 |
申请日期 |
2008.01.06 |
申请人 |
Hepacore Ltd. |
发明人 |
AMIT, Boaz;BARKAY-OLAMI, Hilla;YAYON, Avner |
分类号 |
A61K47/48;A61P43/00;C07K14/75 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|