发明名称 |
NON-IMMUNOGENIC AND NUCLEASE RESISTANT NUCLEIC ACID ORIGAMI DEVICES AND COMPOSITIONS THEREOF |
摘要 |
Nucleic acid origami devices are provided that are non-immunogenic and/or resistant to nucleases, which may be activated by one or more external cues, such as ligands, glucose concentration or electromagnetic fields; or used for attenuation or prevention of internalization of cell-surface receptors or prolongation of shelf-life of active agents. Further provided are methods for treating diabetes and methods for preparing the devices. |
申请公布号 |
EP2986556(A4) |
申请公布日期 |
2016.12.21 |
申请号 |
EP20140785586 |
申请日期 |
2014.04.13 |
申请人 |
Bar-Ilan University |
发明人 |
BACHELET, Ido;ABU-HOROWITZ, Almogit;BEN-ISHAY, Eldad;AMIR, Yaniv;MUNITZ, Ariel;SHAPIRO, Anastasia;SHEMER, Amir;ZALEVSKY, Zeev |
分类号 |
B82Y5/00;A61K48/00;A61P5/00;C12N15/11;C12N15/115;C12N15/87;C12Q1/68 |
主分类号 |
B82Y5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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