发明名称 SYSTEM FOR TRANSDERMAL IONTOPHORETIC DELIVERY OF CHELATED AGENTS
摘要 The present invention provides a composition comprising a chelated iron complex (55) for use in a method of treating iron deficient anaemia in a subject wherein the composition comprising the chelated iron complex is delivered to the subject by iontophoretic transdermal delivery of the composition, the method comprising: applying a patch (10) to the skin of a patient, the patch comprising an electrode (24, 26, 31, 36, 100) and a chelated iron complex (55), the chelated iron complex comprising an iron ion electrostatically bound to a chelating agent and wherein the chelated iron complex (55) comprises a therapeutically effective amount of iron for the treatment of iron deficiency, delivering an electrical current to the skin (20, 30, 24, 31, 21) using the electrode (24, 26, 31, 36, 100); and utilizing the current to transport the chelated complex (55) across the skin (20, 30, 24, 31, 21), wherein the iron is substantially chromogenically unreactive with the skin during transport.
申请公布号 EP3103510(A1) 申请公布日期 2016.12.14
申请号 EP20160174461 申请日期 2010.04.26
申请人 Incube Labs, LLC 发明人 IMRAN, Mir;HASHIM, Mir;PATEL, Sanjay;BERENSON, Ronald J.
分类号 A61N1/30;A61K9/70;A61M37/00 主分类号 A61N1/30
代理机构 代理人
主权项
地址