| 发明名称 |
NEPRILYSIN INHIBITORS |
| 摘要 |
In one aspect, the invention relates to compounds having the formula I: where R1-R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds. |
| 申请公布号 |
EP3099678(A1) |
申请公布日期 |
2016.12.07 |
| 申请号 |
EP20150705859 |
申请日期 |
2015.01.29 |
| 申请人 |
Theravance Biopharma R&D IP, LLC |
发明人 |
FLEURY, Melissa;BEAUSOLIEL, Anne-Marie;HUGHES, Adam D.;LONG, Daniel D.;WILTON, Donna A.A. |
| 分类号 |
C07D405/14;C07C229/34;C07C271/22;C07D231/14;C07D231/18;C07D231/20;C07D233/70;C07D233/90;C07D235/08;C07D237/14;C07D239/34;C07D249/10;C07D249/12;C07D249/18;C07D309/40;C07D319/06;C07D401/04;C07D403/06;C07D405/12;C07D471/04 |
主分类号 |
C07D405/14 |
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