发明名称 がん治療用ワクチン製剤
摘要 [Problem] To provide a method of clearly deriving killer T cells and helper T cells in a cancer treatment vaccine in which the vaccine antibody is a synthetic long peptide which is derived from a tumor-specific antigen protein and/or pathogen-derived protein and which simultaneously contains a CD8-positive, cytotoxic T-cell recognizing epitope and a CD4-poritive, helper T-cell recognizing epitope peptide. [Solution] BY simultaneously dosing an immunopotentiating agent with a conjugate of a hydrophobized polysaccharide (the antigen delivery system) to the synthetic long peptide, it is possible to achieve clear derivation of antigen-specific killer T-cells and helper T-cells from the cancer treatment vaccine in which the synthetic long peptide is the antigen.
申请公布号 JP6041314(B2) 申请公布日期 2016.12.07
申请号 JP20130531390 申请日期 2012.08.30
申请人 国立大学法人三重大学;国立大学法人 東京医科歯科大学 发明人 珠玖 洋;原田 直純;村岡 大輔;秋吉 一成
分类号 A61K39/00;A61K39/39;A61K47/36;A61P35/00 主分类号 A61K39/00
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