| 发明名称 |
Crystalline forms of endo-2,3-dihydro-n-(8-methyl-8- azabicyclo(3.2.1)oct-3-yl)-2-oxo-1h-benzimidazole-1- carboxamide hydrochloride monohydrate and of endo-3-ethyl-2,3-dihydro-n-(8-methyl-8- azabicyclo (3.2.1.)-2-oxo- 1 h-benzimidazole-1- carboxamide hydrochloride monohydrate as 5-ht antagonists |
| 摘要 |
Crystalline monohydrates of endo-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-ben zimidazole-1-carboxamide hydrochloride and of endo-3-ethyl-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-ox o-1H-benzimidazole-1-carboxamide hydrochloride of formula <CHEM> (Compound 2a: R = H> (Compound 2b: R = C2H5> the processes for their preparation and pharmaceutical compositions containing them. <IMAGE> |
| 申请公布号 |
HK1010719(A1) |
申请公布日期 |
2000.05.05 |
| 申请号 |
HK19980111436 |
申请日期 |
1998.10.21 |
| 申请人 |
BOEHRINGER INGELHEIM ITALIA S.P.A. |
发明人 |
ENZO CEREDA;ENRICA DUBINI;ANTOINE EZHAYA;GRAZIA MAFFIONE;MARCO TURCONI |
| 分类号 |
A61K31/46;A61K31/415;A61K31/4184;A61K31/495;A61P1/00;A61P1/08;A61P25/00;A61P25/04;A61P25/06;A61P25/18;A61P25/22;A61P25/24;A61P25/28;C07D235/32;C07D403/12;C07D451/04;C07D451/12;(IPC1-7):C07D;A61K |
主分类号 |
A61K31/46 |
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