| 发明名称 | Method for identifying biologically active oligonucleotides capable of modulating the immune system | ||
| 摘要 | The present invention relates to methods of identifying oligonucleotides capable of modulating the immune system in a mammalian subject, comprising analysis of which tertiary structural type said oligonucleotide adopts, in phosphate-buffered saline solution. Further, the invention provides oligonucleotides identifiable by the methods of the invention and to their use in methods of treating diseases, such as inflammatory diseases, autoimmune diseases, infectious diseases, neurodegenerative diseases and cancer. | ||
| 申请公布号 | US9593337(B2) | 申请公布日期 | 2017.03.14 |
| 申请号 | US201514840628 | 申请日期 | 2015.08.31 |
| 申请人 | INDEX PHARMACEUTICALS AB | 发明人 | Zargari Arezou;Kouznetzov Nicolai;Admyre Charlotte;Von Stein Petra;Von Stein Oliver |
| 分类号 | C12N15/11;C12N15/117;G01N33/68 | 主分类号 | C12N15/11 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. An oligonucleotide selected from the group consisting of SEQ ID NOs: 19, 20, 34, and 76. | ||
| 地址 | Stockholm SE | ||