ANCHORAGE DEVICES COMPRISING AN ACTIVE PHARMACEUTICAL INGREDIENT

摘要

TYRX 3.4-010 An anchorage device 100 comprising a mesh substrate 124 coupled to an implantable medical device 120 is disclosed, where the mesh substrate has a coating 120 comprising a polymer, and the mesh further comprises at least one active pharmaceutical ingredient. The active pharmaceutical agent is designed to elute from the device over time. The mesh substrate can be configured to reduce the mass of the anchorage device such that tissue in-growth and/or scar tissue formation at the treatment site is reduced. In some embodiments, the mesh substrate can be formed with a mesh having a low areal density. In some embodiments, the mesh substrate can include one or more apertures or pores to reduce the mass of the substrate. -60-