GEOGRAPHIC ATROPHY IDENTIFICATION AND MEASUREMENT

摘要

Geographic atrophy of the eye can be detected and measured by imaging the eye at a depth greater than the retinal pigment epithelium (RPE) at a plurality of locations of the eye, for example, using optical coherence tomography (OCT); determining a ratio of the intensities of imaging signals of a retinal layer(s) with respect to the intensity of imaging signals of a sub-RPE layer(s) at each location; determining representative values based at least in part on the determined ratios; generating a map of the representative values; and identifying diseased areas from the map. Contours and binary maps may be generated based on the identified diseased areas. The size and shape of the identified areas may be analyzed and monitored over a period of time.

主权项

1. A method of processing acquired ophthalmic image data including ratios of intensities of backscattered imaging signals for each of a plurality of axial scans and representative values for each of the plurality of axial scans, the representative values being based at least in part on the ratios for the corresponding axial scan, the method comprising:
generating a map of the representative values or ratios; generating seeds of diseased areas; growing a region encompassed by the generated seeds; identifying an area inside the region as diseased; and outputting the generated map with a contour around the regions identified as diseased or outputting a binary mask of the regions identified as diseased.