发明名称 POLYMORPHIC FORMS OF AFATINIB FREE BASE AND AFATINIB DIMALEATE
摘要 The present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereof.
申请公布号 WO2016199076(A3) 申请公布日期 2017.03.09
申请号 WO2016IB53420 申请日期 2016.06.10
申请人 FRESENIUS KABI ONCOLOGY LTD.;CABRI, Walter;LAHIRI, Saswata;MISHRA, Bhuwan Bhaskar;AZIM, Abul;PANDA, Nilendu;BHAVANAM, Poli Reddy;RAY, Krishanu;KACHHADIA, Nikunj;SINGH, Kumber 发明人 CABRI, Walter;LAHIRI, Saswata;MISHRA, Bhuwan Bhaskar;AZIM, Abul;PANDA, Nilendu;BHAVANAM, Poli Reddy;RAY, Krishanu;KACHHADIA, Nikunj;SINGH, Kumber
分类号 C07D407/12;A61K31/517;A61P35/00 主分类号 C07D407/12
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